Morphine Addiction and Abuse | Detox Plus UK

Morphine addiction and abuse is widespread and has many similarities to heroin abuse and addiction. Just because morphine is a prescribed opiate, the devastating effects of addiction carry the same impact as addiction to any illicit opiate.

Did you know that heroin, an opiate derivative, is broken down into morphine by the body once ingested? This is why morphine and heroin-related deaths are recorded as one. The base substance found through drug testing methods cannot differentiate between the two drugs.

In terms of drug poisoning deaths recorded in the UK and indeed most of the world, morphine (and heroin) are the number one illicit substances (1)

opioid addiction

Much like heroin, morphine is incredibly addictive, both in its effects and its quick ability to form tolerance and dependence.

If you or a loved one have a dependence or addiction, you must seek professional help to enable you to safely and successfully stop taking the drug.

What is morphine?

Brand names : MST, Zomorph, Sevredol, Morphgesic, MXL, Oramorph

Morphine is a powerful opioid analgesic and depressant drug, most commonly administered in hospital settings for severe pain or for pain that has become tolerant of other opioids.

Morphine is named after the Greek God of dreams – Morpheus. This is because of the dream-like euphoric state it induces in those that use it.

Morphine is a Class A, Schedule 2 drug in the UK. It is only legal to possess and use with a genuine prescription (2)

Forms of morphine include:

  • Injectable solution
  • Oral tablet and capsules
  • Sublingual tablet
  • Transdermal patch
  • Water-soluble granules
  • Rectal suppository
  • Oral syrup (3)

Morphine is used to treat moderate, severe, and chronic pain. It is also used for pain relief after major surgeries, treatment for cancer-related pain, heart attack and shortness of breath at the end of life patient’s (3)

Who abuses morphine and why?

Some people that can no longer access a genuine prescription for morphine but still crave to feel its effects turn to heroin use as an alternative (4)

Using heroin instead of morphine vastly increases the risk of drug overdose; heroin is an illicit and therefore unregulated drug, containing many other substances and potentially lethal drugs.

Other opioid abuse risks also increase with morphine to heroin, including transmitting blood-borne viruses through shared needles and paraphernalia.

Heroin and morphine have the same base structure once broken down by the body.

Both heroin and morphine are derived from the opium poppy plant and have a very similar chemical structure. Belonging to the drug family of opioids, other powerful prescription opioids include Codeine, Fentanyl and Oxycontin.

How Long Does It Take to Get Addicted to Morphine?

Addiction, even when taken exactly as prescribed and not abused, can quickly develop for several reasons.

As with all opioids, continuous use can create a drug tolerance within as little as 3 to 5 days. Repeated exposure causes the brain cells with opioid receptors attached to gradually become less responsive to opioid stimulation. When tolerance occurs, a person will need to take ever-increasing amounts of the drug to stimulate opioid receptors.

Dependence occurs when a person needs to take the drug to feel normal and not even high. Without it, they experience opioid withdrawal symptoms. Symptoms only occur where tolerance has developed (6)

As a person’s tolerance increases, so will their drug-taking. Thus, unfortunately, dependence only gets progressively worse without the correct medical help and treatment.

Morphine Withdrawal

The symptoms of withdrawal can be so intolerably uncomfortable that they cause a person to continue using to avoid withdrawal.

As a narcotic drug, it is often misused for its pleasurable effects. Those experiencing chronic pain can misuse their medicine, which increases their probability of forming a substance use disorder. An addicted person will compulsively take the drug to get high and be able to function.

Withdrawal can be absolutely crippling. The need to ‘feel ok’ can overtake any desire to stop taking the drug. This is what holds so many addicted to opioids back from getting clean.

Withdrawal really is a double-edged sword. Not only will a dependent person experience physical symptoms but also psychological withdrawal symptoms. In a person that suffers from addiction, they will physically crave the drug to breaking point.

The physical symptoms of withdrawal include:

  • Aches & pains
  • Diarrhoea
  • Stomach cramps
  • Headache
  • Muscle cramps
  • Fever
  • Nausea
  • Vomiting
  • Insomnia
  • Restless legs
  • Lethargy
  • cravings
  • Sweating

The psychological symptoms of  withdrawal include:

  • Anxiety
  • Depression
  • Feeling Irritable
  • Paranoia
  • Dysphoria
  • Cognitive fog
  • Difficulty concentrating
  • Vivid dreams

The longer a person has suffered a dependence and the higher the dose they are tolerant to, the more severe the withdrawal.

As with all addictive drugs, stopping too abruptly, where there is a long-standing dependence, increases the risk of developing PAWS – Protracted Acute Withdrawal Syndrome. PAWS symptoms can last for months, even a year or more in severe cases of dependence and addiction (7)

Suffering from PAWS increases the risk of drug relapse. This is why it is so important to detox safely and correctly.

Stopping abruptly where a dependence has formed will result in the most severe form of opioid withdrawals. However, opioid withdrawals can be life-threatening for a minority of people. This is why rehab is often suggested for heavy or long-standing dependence.

Alternatives to opioid pain medication

pain medication

Alternatives to powerful opioids such as morphine include CBD oils and supplements, pain management therapy, lifestyle change and non-addictive prescription pain relief. However, finding the right solution to a person’s pain needs to take into account more than just their levels of physical discomfort.

Signs of morphine abuse

If you are concerned that you or a loved one may have a problem, there are some signs of abuse to watch out for.

Signs of  abuse include:

  • Taking morphine that does not belong to you
  • Obtaining through illicit means
  • Taking a higher dosage or at an increase frequently other than prescribed
  • Changing the prescribed route of administration to increase the effects
  • Mixing with alcohol to increase its effects
  • Mixing with sedatives, other opioids or depressant drugs to increase its effects
  • Taking prescription morphine when it is no longer genuinely needed
  • Appearing acutely intoxicated by effects
  • Pinpoint pupils
  • Lying to doctors or hospital staff to obtain the drug
  • Stealing morphine from hospital settings or family and friends

Signs of morphine addiction:

  • Using it to prevent opioid withdrawal
  • Using numerous sources to obtain the drug, i.e., different doctors, purchasing from the dark web etc. (risk-taking)
  • Compulsively seeking and taking the drug for its euphoric and relaxant effects (compulsion)
  • Continuing to abuse the drug despite suffering adverse consequences to health, occupation, social or personal relationships (continuation despite negative consequences)
  • Losing control of the amount you use and putting your life at risk (loss of control)
  • Not being able to stop or control use (craving)
  • Loss of interest in previously enjoyed activities, such as hobbies or time spent with family
  • Spends an inordinate amount of times using or recovering from use
  • Continually planning and thinking of ways to get and use morphine (preoccupation)
  • Managing to stop abusing morphine only to start abusing it again (relapse)
  • Progressive use of the drug, i.e. using more, changing the route of administration or mixing with other substances (progression) (5)

Overcoming Morphine Addiction

morphine addiction

To reduce the chances of detox complications developing, dependence treatment should always be overseen by a qualified doctor or consultant.

When a person suffers from an addiction, detoxification is only the first step in recovery. Once detoxed, the person afflicted by addiction will need intensive treatment and rehabilitation to prevent relapse.

At Detox Plus UK, we are experts in treating all forms of drug and alcohol addiction. We offer a compassionate, caring and highly professional approach.

We understand how hopeless addiction can feel and how powerless family and friends feel. At Detox Plus UK, we offer highly qualified and skilled professionals and the latest highly effective addiction treatment methods.

Addiction presents in many forms, to varying degrees of severity and can affect anyone. Therefore, our treatment programmes for addiction account for individuality, which is key to successfully treating the disease of addiction.

At Detox Plus UK, we intricately tailor our drug treatment programmes to treat the whole person, including support and education for the family.


  1. Wide-ranging online data for epidemiologic research (WONDER). Atlanta, GA: CDC, National Center for Health Statistics; 2020. Available at
  2. List of most commonly encountered drugs currently controlled under the misuse of drugs legislation–2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation
  3. Morphine – Strong painkiller to treat severe pain NHS
  4. Prescription opioids and heroin research report NIDA – A subset of people who abuse prescription opioids may progress to heroin use
  5. DSM-IV and DSM-5 Criteria for Substance Use Disorders –
  6. The Neurobiology of Opioid Dependence: Implications for Treatment –

  7. Post-Acute Withdrawal Syndrome PAWS
  8. Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings.



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